Product Category
The Impact of Septum Thickness on Needle Penetration and Sample Integrity
-
May 1, 2022 · We compared 18G, 20G, and 21G needles, which are the most commonly used in practice as they can achieve a good flow of fluid. We found that large-bore needles were the main cause of particle occurrence. The 18G needle yielded a significantly higher number of particles than the 20G and 21G ones (p-value < 0.01).
-
Sep 1, 2005 · In addition to the bleed produced by septum sealing, an even bigger problem is posed by the septum particles that are sometimes deposited in the liner. When a part of the septum is released (for instance, when using an aged septum or a needle with sharp edges), the septum particle will remain in the insert (Figure 4). These particles are in an
-
Jan 10, 2019 · The data are shown in Supplementary Figures and Tables in Fig. S6 for the luer-lock needles and in Fig. S7 for staked needles. To investigate the impact of the angle of injection on needle-penetration force, a 45° angle was compared to a 90° angle relative to the membrane surface, using Terumo 29G × 13 mm TW and BD staked 27G × 8 mm TW
-
14 5.2 Penetration Force 15 5.3 Needle Self-Sealing Capacity 16 5.4 Spike Retention and Sealability Capacity 17 6. PLUNGER FUNCTIONAL SUITABILITY TESTS 18 6.1 Plunger Break-Loose and Glide Forces 19 6.2 Plunger Seal Integrity 20 7. TIP CAP AND NEEDLE SHIELD FUNCTIONAL SUITABILITY TESTS 21 1. INTRODUCTION
-
Bent needles • using the wrong size needle or insert • insert has burrs Plugged needles due to septum coring Lost peak shape • examine inlet end of column with a magnifier and flashlight, looking for discoloration or particles Injection volume too large
-
May 22, 2019 · Sewing needle penetration force and fabric deformation during sewing are effective factors for seam performance. L&M Sewability tester is used for measurement sewing needle penetration force. The L&M Sewability tester enabled consecutive readings of force for penetration of fabric by a selected needle without sewing thread at a rate of 100 rpm.
-
immersion of a sample bottle by hand to just below the surface (t ypically 0.25-0.5m) is satisfactory. Ideally the sampler should be wearing a plastic disposable glove and be standing downstream of where the sample is being collected. Always sample upstream of any other action in the water that may result in stirring up sediment (e g.
-
Jul 1, 2019 · The Standard Test Method for Nondestructive Detection of Leaks in Packages by Vacuum Decay (ASTM F2338 - 09 (2013)) is versatile and can be used on flexible film and inner seals on rigid containers to assess the seal integrity of a water bottle to closure interface. • Bubble emission test. Internal pressure that seals can withstand is
-
Jan 13, 2016 · The coring and fragmentation of elastomer components used in containment of parenteral drug products continues to be a challenge. Many factors influence these phenomena, so it is critical that a pharmaceutical manufacturer understands how a vial system will be used, for example: what is the recommended needle gauge; is it single- or multi-dose; could spikes, vial adapters or closed system
-
Don’t let your septum be the cause of injection failure. The septum you choose for your autosampler vial can impact sample evaporation, sample security, needle bending and blockages, and instrument down time. Don’t let the complexities of septa selection slow you down.
-
Aug 1, 2018 · PFS components were manipulated to systematically assess the contribution of the different sealing areas to CCI, namely rigid needle shield (RNS)/needle, RNS/tip cone, and the individual ribs of a syringe plunger. The polymeric PFS required an equilibrium measurement for accurate container closure integrity testing.
-
PTFE Septa solid disk of 0.010” thick PTFE offers superior chemical inertness against the most aggressive solvents. The thin membrane allows for easy penetration by most needles. PTFE septa are not resealable. They should be used with relatively short cycle times or single injection methods. Pre-slit PTFE/Red Rubber Septa:
-
During the process of puncturing the samples of two materials (Replisil 9N and Formlabs Elastic 50A), force–displacement values were collected, and three predefined parameters evaluated. The differences between the angled/stressed groups and the control group were analyzed.
-
The septum forms a barrier between your sample analyte in the vial and the outside atmosphere. This barrier protects your sample from external contamination while allowing a needle (from a manual or automatic syringe) to enter the vial, and extract the sample for the next stage of separation.
Send Your Inquiry
We not only provide a good product, but also provide high quality service. If you are interested in our products,
you can contact us in the following ways.
you can contact us in the following ways.
